Small molecules & peptides

NITTP

Precursor for [¹⁸F]FMISO ([¹⁸F]fluoromisonidazole)

1-(2'-Nitro-1'-imidazolyl)-2-O-tetrahydropyranyl-3-O-toluenesulfonyl-propanediol; 3-(2-Nitroimidazol-1-yl)-2-O-tetrahydropyranyl-1-O-toluenesulfonylpropanediol

CA index name: 1H-imidazole-1-propanol, 2-nitro-β-[(tetrahydro-2H-pyran-2-yl)oxy]-, 4-methylbenzenesulfonate (ester)

Quality

Research Chemical

Characteristics

Molar mass 425.46

CAS RN [150196-34-2]

Purity ≥ 95 %

  • Yellowish solid

Certificates

CoA: appearance, ¹H and ¹³C NMR spectra

Literature

Oh S.J. et al. Fully automated synthesis of [¹⁸F]fluoromisonidazole using a conventional [¹⁸F]FDG module. Nucl. Med. Biol. 2005, 32, 899–905.

Lim J.L. et al. An efficient radiosynthesis of [¹⁸F]Fluoromisonidazole. Appl. Radiat. Isot. 1993, 44, 1085–1091.

Martin G.V. et al. Noninvasive detection of hypoxic myocardium using [¹⁸F]Fluoromisonidazole and positron emission tomography. J. Nucl. Med. 1992, 33, 2202–2208.

Rasey J.S. et al. Radiolabeled fluoromisoindazole as an imaging agent for tumor hypoxia. Int. J. Radiat. Oncol. Biol. Phys. 1989, 17, 985–991.

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Product No.: 1400Filling amount: 5 mg
Product No.: 1400Filling amount: 10 mg
Product No.: 1400

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