Small molecules & peptides
NITTP (GMP)
Precursor for [¹⁸F]FMISO ([¹⁸F]fluoromisonidazole)
1-(2'-Nitro-1'-imidazolyl)-2-O-tetrahydropyranyl-3-O-toluenesulfonyl-propanediol; 3-(2-Nitroimidazol-1-yl)-2-O-tetrahydropyranyl-1-O-toluenesulfonylpropanediol
CA index name: 1H-imidazole-1-propanol, 2-nitro-β-[(tetrahydro-2H-pyran-2-yl)oxy]-, 4-methylbenzenesulfonate (ester)
Quality
GMP Product
Characteristics
Molar mass 425.46
CAS RN [150196-34-2]
Purity ≥ 97 %
- Yellowish solid
Certificates
CoA: appearance, NMR and IR spectra (identity), HPLC (purity), GC (residual solvents), microbiology test
Literature
Oh S.J. et al. Fully automated synthesis of [¹⁸F]fluoromisonidazole using a conventional [¹⁸F]FDG module. Nucl. Med. Biol.2005, 32, 899–905.
Lim J.L. et al. An efficient radiosynthesis of [¹⁸F]Fluoromisonidazole. Appl. Radiat. Isot.1993, 44, 1085–1091.
Martin G.V. et al. Noninvasive detection of hypoxic myocardium using [¹⁸F]Fluoromisonidazole and positron emission tomography. J. Nucl. Med.1992, 33, 2202–2208.
Rasey J.S. et al. Radiolabeled fluoromisoindazole as an imaging agent for tumor hypoxia. Int. J. Radiat. Oncol. Biol. Phys. 1989, 17, 985–991.
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| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/7343e79f-fa6a-4936-ac80-e09c822f2510 | Precursor | Product No.: 1402 | Filling amount: 10 mg | ||
| /products/small-molecules-and-peptides/chemical/7343e79f-fa6a-4936-ac80-e09c822f2510 | Precursor | Product No.: 1402 |
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